Colonoscopy Superior to CTC for Post–Cancer Resection Surveillance

In a prospective study of 231 patients with surgically resected colorectal cancer who were undergoing surveillance at 1 year postresection, computed tomography colonography (CTC) was performed with subsequent same-day colonoscopy using segmental unblinding of the colonoscopists to the CTC results. The primary endpoint was detection of patients with polyps ≥6 in size.

Using CTC, operators identified 16 of 36 patients (44%) with adenomas or serrated class lesions ≥6 mm in size with 94% specificity. The sensitivity of CTC for patients with polyps ≥10 mm was 77%.