Improving Risk Stratification for Patients with Intracranial Atherosclerosis

Patients with additional atherosclerotic diseases had different risks for major adverse cardiac events than those with intracranial atherosclerosis alone.

Intracranial atherosclerotic disease (ICAD) is one of the leading causes of ischemic stroke. ICAD is particularly common in African American and Asian patients with ischemic stroke. These authors attempted to identify a consecutive group of patients with ICAD and determine whether disease in other vascular beds affects prognosis. The primary study outcome was major adverse cardiovascular events (MACE), including stroke, myocardial infarction, vascular death, and major peripheral vascular events.

Overall, 403 patients (74% men; mean age, 63 years) were enrolled in the study. Significant ICAD, defined as ≥50% stenosis in a major intracranial vessel, was found in 36.2% of patients. Among symptomatic patients with ICAD, the estimated 4-year risk…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Improving Risk Stratification for Patients with Intracranial Atherosclerosis

Topics

Reviewing Author