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Blood and tissue samples are now being used to identify specific treatment regimens to treat various cancers. One approach is growing organoids, macroscopic organ-like structures, from a microscopic sample of a tumor. Organoids can be used to study a patient's tumor, including parenchymal and stromal elements, then be used as a “test bed” to help identify tumor- and patient-specific treatments via ex vivo testing. Growing organoids from pancreatic cancers sampled via endoscopic ultrasound (EUS) has been shown to be feasible.
In the current prospective pilot study, researchers evaluated the rate of successful isolation of organoids within 2 weeks of acquiring pancreatic ductal adenocarcinoma tumor tissue. Among 37 patients, 38 pancreatic aden…