Preoperative exercise reduced postoperative complication rates and length of hospital stay.
Preoperative exercise has been evaluated in several clinical trials, but its effectiveness in reducing postoperative complications remains unknown.
To examine this issue, investigators performed a meta-analysis of data from 13 randomized controlled trials (RCTs) or quasi-randomized controlled trials (qRCTs) involving 806 patients (median age, 63.3 years) with six different primary tumor types and surgeries. The duration of most preoperative exercise interventions was 2 weeks (range, 1 to 4 weeks). Of note, approximately half the trials had at least one feature with a high risk of bias.
For patients undergoing liver resection for colorectal cancer or surgery for colon, esophageal, lung, oral, and prostate cancer, the effectiveness of preoperat…
Reviewing Author
DisclosuresConsultant/Advisory BoardGenentech; AstraZeneca; Boehringer-Ingelheim; Bristol-Myers Squibb; Clinical Care Options; Heron; Takeda; Ariad; MedIQ; Targeted Healthcare Communications; Novartis; OncLive; Roche; TRM Oncology
RoyaltiesUpToDate
Grant/Research SupportMedimmune; NIH/National Cancer Institute; Millennium; Genentech; Polaris Pharmaceuticals; Seattle Genetics; Boehringer-Ingelheim Pharmaceuticals; SWOG–Hope Foundation; American Cancer Society; Department of Defense; GlaxoSmithKline Pharmaceuticals; Merck; Eli Lilly; Takeda; Bristol-Myers Squibb
DisclosuresConsultant/Advisory BoardGenentech; AstraZeneca; Boehringer-Ingelheim; Bristol-Myers Squibb; Clinical Care Options; Heron; Takeda; Ariad; MedIQ; Targeted Healthcare Communications; Novartis; OncLive; Roche; TRM Oncology
RoyaltiesUpToDate
Grant/Research SupportMedimmune; NIH/National Cancer Institute; Millennium; Genentech; Polaris Pharmaceuticals; Seattle Genetics; Boehringer-Ingelheim Pharmaceuticals; SWOG–Hope Foundation; American Cancer Society; Department of Defense; GlaxoSmithKline Pharmaceuticals; Merck; Eli Lilly; Takeda; Bristol-Myers Squibb