Endovascular Treatment for Acute Stroke in Routine Practice

A registry study begun after the randomized MR CLEAN trial shows how real-world outcomes compare with those in the trial.

Several clinical trials have been published since 2015 demonstrating the value of endovascular therapy (EVT) for patients with large vessel occlusion (LVO) in the anterior circulation. These trials typically had detailed inclusion and exclusion criteria regarding baseline imaging characteristics and time from symptom onset. One of the trials (MR CLEAN) was performed exclusively within the Netherlands. The MR CLEAN authors have now evaluated EVT outcome in “routine practice” by comparing results of patients in the MR CLEAN Registry with the interventional patients treated in the randomized trial. The registry had 1488 patients (median age, 71; median NIH Stroke Scale score, 16), compared with only 233 in the trial's intervention arm. Patient…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Endovascular Treatment for Acute Stroke in Routine Practice

Topics

Reviewing Author