New Guideline for Endoscopic Ablation of Barrett Esophagus

Endoscopic ablation is recommended for both low-grade and high-grade dysplasia as well as intramucosal cancer after resection of visible lesions.

Sponsoring Organization: American Society for Gastrointestinal Endoscopy

Target Audience: Gastrointestinal endoscopists

Background and Objective

The histologic progression of Barrett esophagus (BE) over time — from intestinal metaplasia through low-grade dysplasia (LGD), high-grade dysplasia (HGD), and intramucosal cancer (IMC) — allows for potential intervention at these stages to prevent invasive esophageal adenocarcinoma (EAC). While prior general guidelines on BE have endorsed endoscopic resection and endoscopic eradication therapy (EET) for dysplastic BE and IMC, this is the first guideline to focus specifically on this topic.

Key Recommendations

Acquire confirmation of LGD or HGD by an expert gastrointestinal pathologist before performing …

Reviewing Author

David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)

Disclosures

Nothing to disclose