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The popularity of e-cigarettes has led to a sharp rise in the number of young children exposed to liquid nicotine, a concentrated form that can cause serious medical outcomes, including death. Using data from the National Poison Data System, researchers evaluated trends in exposures and the effect of U.S. federal legislation requiring child-resistant packaging (the Child Nicotine Poisoning Prevention Act) that took effect in July 2016.
There were 8269 reports of exposure to liquid nicotine in children <6 years old from 2012 to 2017. Of these exposures, 93% were by ingestion and 84% were in children <3 years old. One quarter of exposed children experienced one or more clinical effects, with rare severe effects including coma, seizure, respira…