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The role of stress as a risk factor in cardiometabolic disease still needs clarification. These investigators linked individual-level data on prevalent cardiometabolic diseases (coronary heart disease, stroke, or diabetes) from seven European cohort studies to data from national death registries to examine the association between work stress (job strain or effort–reward imbalance at work) and mortality.
In multivariable-adjusted analyses, mortality among men with cardiometabolic disease was significantly higher in people with job strain than in those without (hazard ratio [HR], 1.68). The excess mortality associated with job strain was almost as great as that associated with current smoking (compared with never/former smoking) and was greate…