A small study yields insights into a little-understood phenomenon.
Perioperative acute coronary syndrome is well known, but its underlying etiology remains obscure. To learn more, investigators in a retrospective single-center cohort study identified 146 patients who underwent coronary angiography for acute coronary syndrome within 30 days of noncardiac surgery.
The event occurred after emergency surgery in 8% of the cohort. The vast majority had a non–ST-elevation myocardial infarction (80%). The event was clinically silent in 22% and occurred within 3 days of the operation in 63%. The 30-day death rate was 7%.
Based on coronary angiography, events were classified as demand ischemia (type 2 myocardial infarction [MI]) in 73% or as related to an acute thrombosis (type 1 MI) in 25%. Nonobstructive coronary ar…
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association