To Prevent Contrast-Induced Kidney Injury, Bioimpedance-Guided Therapy Might Help

In patients undergoing cardiac catheterization, contrast-induced acute kidney injury is both common and associated with adverse outcomes and high costs. Hydration can reduce the risk for injury, but determining the hydration status of a patient is often difficult — and complications can arise with a hydration strategy. Investigators, who noted no conflicts of interest, evaluated a bioimpedance-guided hydration strategy (NCT02225431).

Of 1018 patients undergoing coronary angiography and without heart failure, 303 patients had low total body fluid level based on bioimpedance (mean age, 71; 32% women) and were randomized to standard-volume isotonic saline (1 mL/kg/hour) or double that amount. Infusions lasted for 12 hours before and after the p…