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Evidence suggests that the prevalences of alcoholic and nonalcoholic fatty liver diseases are increasing. In this observational cohort study, investigators examined trends in deaths caused by cirrhosis and hepatocellular carcinoma in the U.S.
From 1999 through 2016, annual deaths increased from 20,700 to 34,200 for cirrhosis and from 5100 to 11,100 for hepatocellular carcinoma. Compared with women, men had age-adjusted, cirrhosis-related and hepatocellular carcinoma–related mortality that was twofold and fourfold higher, respectively. Age-adjusted death due to cirrhosis was highest among Native Americans, followed by Hispanics and whites. Age-adjusted death due to hepatocellular carcinoma was highest among people of Asian and Pacific Islande…