Mortality in Takotsubo Syndrome Depends on the Trigger

Five-year mortality was substantially worse in patients with physical triggers rather than with emotional triggers.

Takotsubo syndrome (TTS) is generally considered to have a more favorable prognosis than acute coronary syndrome (ACS). However, its true long-term prognosis is not completely understood, and the relations between triggering factors for TTS and outcomes is unknown. To better understand TTS, researchers analyzed data on 1613 patients with TTS from the International Takotsubo Registry.

As in previous analyses, almost all TTS patients were women (90%), with an even higher percentage among those with emotional triggers (95%). In the cohort, 485 (30%) had an emotional trigger, and 630 (39%) had a physical trigger (532 cases [33%] associated with medical conditions, procedures, or physical activities and 98 [6%] associated with acute neurologic ev…

Reviewing Author

Karol E. Watson, MD, PhD, FACC

Disclosures

Consultant/Advisory BoardBoehringer Ingelheim; Amgen; Novartis; Lilly; Amarin

Speaker’s BureauBoehringer Ingelheim

Grant/Research SupportNIH

Editorial BoardsCirculation (Associate Editor)