In eight HIV clinics across the U.S., virologic suppression increased from 32% in 1997 to 86% in 2015. Older age and use of an integrase inhibitor–based regimen were associated with lower odds of having a detectable viral load.
As antiretroviral therapy has improved, viral suppression rates have also improved among persons living with HIV (PLWH). Investigators studied trends of viral suppression (HIV-1 viral load < 400 copies/mL) from 1997 through 2105 among 31,930 PLWH cared for in eight clinics across the U.S. Study participants were mostly men (82%) and 55% were nonwhite.
Viral suppression increased from 32% in 1997 to 86% in 2015. Patients with viral suppression were older (46 vs. 41 years) with a 5% increase in viral suppression for each decade of age. The likelihood of viral suppression was also 3% higher for men than women, 8% lower in black than white PLWH, and 6% lower in those who had acquired HIV through injection drug use, compared with men who have sex…
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)