Blue Laser Imaging-Bright Can Improve Detection of Early Gastric Cancer

In a prospective, randomized study, blue laser imaging-bright detected 93% of early gastric cancers, compared with 50% for white-light imaging.

Surveillance endoscopy for atrophic gastritis with intestinal metaplasia or after endoscopic resection of an early gastric cancer is a common practice in many areas of the world with a high prevalence of gastric cancer. Current endoscopic screening is imperfect as early disease can be missed on white-light imaging (WLI). Blue laser imaging (BLI)-bright is a new image-enhanced endoscopy modality with two laser wavelengths that allow for narrow-band light imaging.

This industry-supported work took place in two Japanese hospitals. Some 600 patients undergoing surveillance endoscopy for early gastric cancer were randomized to imaging, first with WLI or BLI-bright, followed by the other modality. The primary detection rate of BLI-bright was great…

Reviewing Author

John R. Saltzman, MD

Disclosures

Consultant/Advisory BoardIterative Scopes

Editorial BoardsGastrointestinal Endoscopy; UpToDate

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology (Trustee)

OtherVice President of Medical Affairs, 1Globe Health Institute