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Idiopathic carpal tunnel syndrome (CTS) is frequently associated with pathological changes in the carpal tunnel subsynovial connective tissue. It can be treated with nonsurgical methods (analgesics, wrist splints, corticosteroid injection, and physiotherapy) or surgical techniques. Injection of 5% dextrose (D5W) has shown benefits for this condition and has been shown to be a safe procedure. To test whether perineural injection of D5W is more effective than corticosteroids for CTS with respect to pain and disability, researchers screened 60 patients diagnosed with CTS and randomized 54 of them (total of 60 wrists) to receive dextrose or steroid injections (27 per group). The patients received one perineural injection with 5 cc of D5W or 3 c…