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Some reports suggest excess risk for diabetic ketoacidosis (DKA) in cannabis users with type 1 diabetes. This retrospective cohort study took place at a diabetes treatment center in Colorado, where recreational and medical marijuana are legal. Researchers asked 450 adults with type 1 diabetes (mean age, 35; mean duration of diabetes, 19 years) about cannabis use and hospitalization for DKA in the previous year; 30% of these patients were cannabis users, half used the substance at least twice weekly, and half had used cannabis for longer than 3 years. About 40% were considered to have possibly hazardous levels of use or cannabis use disorders.
Based on patients' reports of hospitalization for ketoacidosis (validated by medical record review),…