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Ventricular tachycardia (VT) frequently complicates the care of patients with cardiomyopathies and implantable cardioverter–defibrillators. Despite improvements in ablative tools and techniques, many patients continue to suffer from VT. An initial report of an experimental noninvasive technique, stereotactic body radiotherapy, in 5 patients surprised many (NEJM JW Cardiol Feb 2018 and N Engl J Med 2017; 377:2325). A single-arm, phase I/II study in 19 patients now provides further data.
Of these 19 patients, 17 had refractory VT and 2 had premature ventricular contractions associated with cardiomyopathy; all patients were unresponsive to previous catheter ablation (n=16) or were unable to undergo ablation because of mechanical valves (n=3). T…