Magnetic Resonance Elastography to Predict Hepatocellular Carcinoma After Eradication of Chronic HCV Infection

In chronic hepatitis C virus (HCV) with advanced fibrosis, the risk for hepatocellular carcinoma (HCC) is likely reduced with eradication of infection. However, the risk is not zero, and so these patients should continue screening. It is unclear whether screening intervals can be extended or screening even stopped in certain patients.

This study evaluates the relationship between liver stiffness measured by magnetic resonance elastography (MRE) and the development of HCC after sustained virologic response. Liver stiffness was measured at 12 weeks after end of treatment, and patients were followed for a minimum of 1 additional year. Ultrasound and lab testing were performed every 3–6 months.

The study cohort comprised 304 patients; 163 had und…