Epidemiology of Neonatal Group B Streptococcal Disease in the U.S., 2006–2015

Late-onset group B streptococcal disease has outpaced early-onset disease.

Neonatal group B streptococcal disease (GBS) is a major cause of infant morbidity and mortality. The implementation of prenatal screening and prophylaxis for GBS colonization has dramatically reduced the incidence of early-onset disease (EOD), which occurs during the first week of life. However, this prevention strategy has not reduced the incidence of late-onset disease (LOD).

To better define the epidemiology of EOD and LOD, investigators have analyzed 9 years of data (2006–2015) from the multistate Active Bacterial Core surveillance program, which captures approximately 10% of U.S. born infants and in 2015 included 439,000 live births. Key findings included the following:

1277 cases of EOD and 1387 cases of LOD were identified.
Incidence of…

Reviewing Author

Deborah Lehman, MD

Disclosures

Nothing to disclose

Deborah Lehman, MD

Disclosures

Nothing to disclose

Epidemiology of Neonatal Group B Streptococcal Disease in the U.S., 2006–2015

Topics

Reviewing Author