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Low-volume bowel preparation (“prep”) regimens are attractive because they are better tolerated by patients and have comparable effectiveness with standard-volume, 4-liter regimens. However, it is unknown whether low-volume preps are associated with better participation in colonoscopy-based screening programs. To find out, investigators randomized over 13,500 Poland residents to prep regimens of 0.3 L sodium picosulfate with magnesium citrate or standard-volume (4 L) polyethylene glycol (PEG) and then invited them to undergo colonoscopy as part of a population-based screening program. Results were as follows:
Participation rates were not significantly different between groups (16.6% for low-volume vs. 15.5%).
Participation was more likely in …