Delays to Acute Stroke Treatment and Odds of Reperfusion

Odds of reperfusion decrease with increasing time from admission and from imaging to treatment with mechanical thrombectomy.

Since 2015, acute stroke intervention with mechanical thrombectomy (MT) has been an important treatment modality for patients presenting with acute ischemic stroke and evidence of a large-vessel occlusion. Several analyses have shown that “time is brain,” and more-rapid treatment is associated with an improved likelihood of better clinical outcome.

To examine whether the speed of starting the interventional procedure is associated with improvement in the chance of brain reperfusion, investigators assessed pooled data from seven interventional trials totaling 728 patients (mean age, 65; 47% women) with an internal carotid or middle cerebral artery occlusion. The median NIH Stroke Scale score was 17, representing severe stroke deficits. Median…

Reviewing Author

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Seemant Chaturvedi, MD

Disclosures

Consultant/Advisory BoardBayer Pharmaceuticals; Novartis

Grant/Research SupportNational Institute of Neurological Disorders and Stroke

Editorial BoardsNeurology; Stroke

Delays to Acute Stroke Treatment and Odds of Reperfusion

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Reviewing Author