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Clinical remission is attainable in as many as 50% of patients with rheumatoid arthritis (RA) by using currently approved drugs and changing therapy depending on disease activity. Some experts have proposed use of magnetic resonance imaging (MRI) to define disease activity and guide therapeutic interventions — a very costly strategy. Danish researchers compared MRI versus conventional disease-activity scores to guide treatment in 200 patients with seropositive erosive RA in clinical remission. Patients were randomized to an MRI group or a conventional (control) group with evaluations in both groups every 4 months. The treatment target in the MRI group was remission, defined as absence of bone marrow edema, combined with clinical remission (…