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Patients with ischemic stroke or transient ischemic attack (TIA) are still at increased risk for recurrent stroke and future vascular events despite the effectiveness of current preventive therapies. New strategies are needed to further improve outcomes. Diabetes is an important risk factor for stroke; 50% of stroke patients without diabetes have insulin resistance. This condition is associated with increased blood pressure and high cholesterol levels. Unfortunately, insulin resistance is not commonly measured in clinical practice.
In this post hoc analysis of the IRIS randomized clinical trial, the objective was to analyze the effects of pioglitazone in patients with good adherence and the intention-to-treat effects of pioglitazone in patie…