Eosinophilic Esophagitis and Inflammatory Bowel Disease Often Coexist

U.S. population-based data show elevated incidence of EoE in patients with IBD and vice versa.

Eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) are immune-mediated diseases with some potential intersections in pathogenesis and epidemiology. In a longitudinal analysis of insurance claims data from over 130 million U.S. patients, investigators found a threefold to fivefold increased risk for EoE in patients with Crohn disease or ulcerative colitis compared with individuals without either disease. There was also a threefold to sixfold increased risk for IBD in patients with known EoE compared with individuals without EoE. IBD complications were slightly more common in patients with concurrent EoE, while conversely, patients with EoE were less likely to have complications if they had concurrent IBD. The latter might be…

Reviewing Author

Kenneth R. DeVault, MD

Disclosures

Consultant/Advisory BoardPhathom Pharmaceuticals

Grant/Research SupportIronwood Pharmaceuticals

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology Education Universe (Co-Editor)

Kenneth R. DeVault, MD

Disclosures

Consultant/Advisory BoardPhathom Pharmaceuticals

Grant/Research SupportIronwood Pharmaceuticals

Leadership Positions in Professional SocietiesAmerican College of Gastroenterology Education Universe (Co-Editor)

Eosinophilic Esophagitis and Inflammatory Bowel Disease Often Coexist

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Reviewing Author