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Stressful life events (e.g., death of a loved one, illness, trauma) have been associated with excess risk for cardiovascular disease (CVD). In this study from Sweden, researchers used national registries to identify 140,000 patients with diagnosed stress-related disorders (e.g., post-traumatic stress disorder, acute stress reaction, adjustment disorder) from 1987 through 2013. The investigators also identified a sibling cohort (170,000 full siblings without stress-related diagnoses) and a population cohort (10 randomly selected unexposed people for each exposed patient, matched by birth year and sex). Median follow-up times were ≈7 years in each group; results were adjusted for multiple variables.
Patients with stress-related disorders had a…