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Notice of retraction: The article summarized here has been retracted by the journal after the authors informed the editors that they “uncovered irregularities and deviations from the approved protocol related to the work reported in [the] article.” The retraction can be seen here: https://www.biologicalpsychiatryjournal.com/article/S0006-3223(22)01812-1/fulltext
Older depressed patients can experience slowing of gait and processing speed, which do not respond to standard antidepressants. To assess a novel approach to these problems, researchers openly treated 36 mildly-to-moderately depressed people (mean age, 75) with an increasing number of doses of 150 mg of levodopa combined with 37.5 of the decarboxylase inhibitor carbidopa, which slows…