Are Stenotic Bicuspid Aortic Valves Suitable for TAVR?

A registry-based study demonstrates similar 1-year outcomes with transcatheter aortic valve replacement in bicuspid and tricuspid valves.

Although bicuspid aortic valves (BAVs) are present in up to 50% of relatively young patients with aortic stenosis, these have been excluded from randomized studies of transcatheter aortic valve replacement (TAVR). To learn about outcomes with TAVR in BAV, investigators conducted a manufacturer-supported observational study using data from the Society of Thoracic Surgeons/American College of Cardiology TVT Registry.

Of 92,236 registry patients undergoing TAVR with a third-generation balloon-expandable prosthesis, the investigators culled 2691 propensity-matched pairs of patients, including 469 pairs with Medicare-linked 1-year outcomes. Patients with BAV were younger than those with tricuspid valves (median age, 73 vs. 82), more likely men (6…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)