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Established treatments for post-traumatic stress disorder (PTSD) include medications — especially selective serotonin reuptake inhibitors (SSRIs) — and psychotherapies. These researchers conducted a pairwise meta-analysis (directly comparing studies of 2 or 3 treatments) and a network meta-analysis (e.g., comparing treatments A versus B and B versus C, with inferences about A versus C) of 12 randomized, controlled trials involving 922 participants with PTSD and examining outcomes with psychotherapy (including cognitive-behavioral therapy, exposure therapy, prolonged exposure, seeking safety, and eye-movement desensitization and reprocessing), pharmacotherapy, and their combination.
At the end of treatment, the three conditions did not differ…