Afebrile neonates presenting with a history of fever who remained afebrile during hospitalization were less likely than febrile neonates to have serious bacterial infections.
The risk for serious bacterial infection (SBI; bacteremia, bacterial meningitis, urinary tract infection) or invasive bacterial infection (IBI; bacteremia, bacterial meningitis) in febrile infants ≤28 days of age is as high as 14%. Therefore, most well-appearing febrile infants in the first month of life are hospitalized typically for 24 to 48 hours until blood, cerebrospinal fluid, and urine bacterial cultures are proven negative.
Investigators have now conducted a retrospective study to determine rates of SBI and IBI in 931 infants (≤28 days of age) who presented to an emergency department at a single center. Of these, 60% were febrile at presentation (FP), 30% were afebrile at presentation with a history of fever but no subsequent fever d…
Reviewing Author
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)