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During hospitalization, patients frequently have transient elevations in blood pressure (BP), which result in modification of their outpatient antihypertensive regimens at discharge. No studies have been designed to evaluate whether this practice improves outcomes. Researchers at a Veterans Affairs Hospital in California performed a retrospective propensity-matched cohort study of more than 4000 older, mostly male patients who either received or did not receive up-titration of antihypertensive medications at discharge, after admission for one of three noncardiac conditions (pneumonia, urinary tract infection, or venous thromboembolism).
At 30 days, patients who received intensification of their antihypertensive regimens had excess risks for …