Metabolic Surgery Is Associated with Fewer Adverse Cardiovascular Events in Diabetic Patients

Metabolic surgery (surgery that induces weight loss and alters gastrointestinal and glucose physiology) improves diabetes control, but data on changes in risk for adverse cardiovascular events are sparse. Cleveland Clinic researchers identified 2287 patients with type 2 diabetes who underwent metabolic surgery (nearly all Roux-en-Y gastric bypasses or sleeve gastrectomies) and matched these patients on 37 variables to 11,435 patients who did not undergo metabolic surgery. Two thirds of patients were women; median age was 54, and median body-mass index was ≈44 kg/m².

Median follow-up was 4 years, but the researchers calculated 8-year estimated outcomes. The 8-year cumulative incidence of major adverse events (i.e., all-cause mortality, corona…