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Nonsteroidal anti-inflammatory agents are effective in reducing pain but may raise blood pressure (BP) in adults with chronic hypertension. To evaluate whether ibuprofen affects BP in women with hypertensive disorders of pregnancy and mild hypertension during the immediate postpartum period, researchers conducted a double-blind randomized trial involving 61 such women; of these, 31 received ibuprofen (600 mg every 6 hours) and 30 received acetaminophen (650 mg every 6 hours). BP was assessed every 4 hours, yielding an average of 17 measurements per participant prior to hospital discharge.
Postpartum average arterial pressure did not differ between groups. There was no difference in the proportion of participants who requested additional brea…