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The histology of colorectal polyps can be accurately predicted during endoscopy using validated criteria, with pathology analysis as the gold standard. However, in a recent study, 15% of polyps ≤3 mm predicted to be adenomas with high confidence were interpreted as normal tissue on pathology (Endoscopy 2019 51; 221).
In the current study, investigators assessed whether a validated artificial intelligence (AI) clinical decision support tool could resolve such discrepancies. The dataset included 644 polyps ≤3 mm with previous high-confidence endoscopic diagnosis of adenoma. The results were as follows:
The rate of discordance between endoscopic and pathologic diagnoses was 29%, with most polyps interpreted as hyperplastic polyp or normal mucosa…