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Cognitive complaints in nonelderly adults without medical or neurologic causes are challenging for psychiatrists. To catalog possible sources of these complaints, researchers conducted a systematic review of 249 studies describing people with cognitive symptoms but not found to have dementia. Most studies excluded people with chronic fatigue syndrome, fibromyalgia, and major psychiatric, medical, and neurologic illnesses.
Cognitive symptoms were common, with a community prevalence of 30%; no specific cause was found in 24% of people seeking evaluations in memory clinics. In these disparate studies, people with subjective worry about cognition typically provided a paradoxically detailed history and had nonprogressive cognitive symptoms that o…