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Neuroimaging studies have shown functional and structural alterations of different brain areas in migraine patients, raising new questions. How do these regions interact with each other? Does a unique network enclose all these brain areas? Are these neuroimaging findings migraine specific?
To address these questions, researchers used resting-state functional MRI data from 1000 healthy controls and looked at functional connectivity of brain areas that previously showed consistent volumetric alterations in migraine patients with and without aura: brain regions involving the right cerebellum, left cingulate, and bilateral frontal gyrus. They also looked at connectivity of brain areas involved in chronic pain conditions and Alzheimer disease as …