In the largest series to date of patients hospitalized with 2019-nCoV pneumonia in Wuhan, China, hospital-associated transmission was common, 26% required intensive care, and mortality was 4.3%. In a smaller series from Beijing, illness was milder, and no deaths were reported.
The first reports of the clinical characteristics of 2019 novel coronavirus (2019-nCoV) were recently published (NEJM JW Infect Dis Feb 2020 and Lancet 2020 Jan 24; [e-pub]; Lancet 2020 Jan 24; [e-pub]; and N Engl J Med 2020 Jan 24; [e-pub]). Now, a large case series from Wuhan and a much smaller series from Beijing add to our understanding.
Wang and colleagues report that, among 138 hospitalized patients in Wuhan, median age was 56 (range, 22–92), 54.3% were men, and close to half had comorbidities, including hypertension, diabetes, and cardiovascular diseases. The most common symptom at onset was fever (98.6%), followed by fatigue and dry cough in approximately half and myalgias and dyspnea in one third each. Notably, 10% presented with di…
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)