Loading...
Monoclonal gammopathy of undetermined significance (MGUS) usually is discovered as an incidental finding on serum protein electrophoresis (SPEP). In this study from Mayo Clinic Rochester, researchers examined various aspects of diagnosis and follow-up of 329 patients (mean age, 73) who received diagnoses of MGUS between 2011 and 2014.
Among the initial tests (presumably SPEP in most cases) that resulted in diagnoses of MGUS, 37% were ordered by generalists and 63% by a broad range of specialists. The most common indications for testing were neuropathy (19%), renal disease (14%), anemia (13%), and musculoskeletal disorders (13%). Follow-up intervals varied considerably among both hematologists and non-hematologists. Intensity of follow-up did…