Trial of Endovascular Therapy for Venous Sinus Thrombosis

Cerebral venous thrombosis (CVT) is much less common than arterial ischemic stroke and tends to occur in younger patients and in those with hypercoagulable states. Systemic anticoagulation is recommended for CVT patients. However, because some patients have poor outcomes, including death, the use of endovascular therapy (EVT) has been explored in single-center studies. Now, investigators present results of a multicenter, randomized, open-label, blinded-endpoint study comparing EVT plus medical therapy with medical therapy alone. Patients had CVT plus at least one adverse prognostic factor (e.g., mental status disorder, coma, intracerebral hemorrhage [ICH], or deep venous involvement). Medical therapy included anticoagulation. EVT technique,…