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Degeneration of the larval cysts of Taenia solium in the brain is associated with inflammation and the clinical outcomes of neurocysticercosis (NCC). Those outcomes include brain calcifications, which are associated with seizures, headaches, and cognitive dysfunction. Investigators reviewed characteristics associated with the development of calcifications at 1-year post enrollment in NCC patients from three prospective trials. All subjects had at least one viable cyst at baseline that resolved and had MRIs at baseline and 6 months, and computed tomography (CT) at 12 months.
Of 220 patients, 147 met inclusion criteria. The mean age was 32 years, and 64.6% were male. At 1-year follow-up, 38% of the cysts had calcified. The presence of calcific…