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Cerebral venous thrombosis (CVT) can be a challenging diagnosis because the clinical presentation is variable. Headache, seizures, altered mental status, and stroke-like symptoms may occur in any combination in different patients. To help clinicians diagnose CVT, investigators conducted a study of 359 patients at two emergency departments who presented with headache and additional CVT-associated symptoms, such as seizures, focal deficits, altered consciousness, or unexplained papilledema.
The researchers devised a clinical CVT risk score based on six variables; seizure (4 points), known thrombophilia (4 points), oral contraceptive use (2 points), duration of symptoms for >6 days (2 points), worst headache ever (1 point), and focal neurologic…