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Transient global amnesia (TGA) is a reversible, benign, mostly nonrecurrent clinical syndrome of anterograde amnesia lasting up to 24 hours in the absence of other neurologic symptoms. The etiology and pathogenesis of TGA is uncertain, although several causes have been suggested including ischemia, epileptic seizures, migraine, venous congestion, and psychological disturbance. Diffusion-weighted imaging (DWI) aids the diagnosis of TGA and is now widely use in clinical practice. To show how hippocampal DWI lesions may support the diagnosis of TGA, investigators conducted a retrospective observational study of 390 patients with TGA. Lesions in the hippocampus were analyzed with regard to size, location, number of lesions, and different levels…