Which Uterine-Sparing Surgical Treatment for Symptomatic Fibroids Improves Quality of Life Most?

Women with symptomatic fibroids who want to avoid hysterectomy can be treated with myomectomy, uterine artery embolization (UAE), radiofrequency or high-frequency ultrasound fibroid ablation, endometrial ablation, a levonorgestrel-releasing intrauterine device, or oral elagolix plus norethindrone acetate plus estradiol (Oriahnn). Which surgical procedure works best? Investigators in the U.K. randomized 254 women (mean age, 42; mean BMI, 28 kg/m²) with symptomatic uterine fibroids to myomectomy or UAE. Participants reported quality of life (QOL) using the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire (score range, 0–100), the European Quality of Life 5-Dimension 3-Level (EQ-5D-3L) questionnaire (range, -0.59–1.00), and …