Loading...
How do blood pressure (BP) readings in clinical trials compare with those obtained in routine clinical practice? To answer this question, researchers compared BP data from the Systolic Blood Pressure Intervention Trial (SPRINT) and BP data from SPRINT patients' routine clinical visits. In SPRINT (NEJM JW Gen Med Dec 15 2015 and N Engl J Med 2015; 373:2103), high-risk patients were randomized to intensive or standard treatment (systolic BP goal, <120 mm Hg or <140 mm Hg, respectively.
Participant-level SPRINT and electronic health record data were available for 3074 adults (age, ≥50; mean age, 69) with hypertension. At baseline, mean BP was 138/77 mm Hg. During follow-up of 3.2 years, median numbers of BP readings taken during SPRINT and rout…