Extended-Spectrum Beta-Lactamase–Producing Bacteria in Patients Hospitalized for UTI

In this multicenter study, these organisms were identified in 17% of patients, and administration of an in vitro active antibiotic was often delayed.

To determine the prevalence of extended-spectrum beta-lactamase (ESBL)–producing Enterobacteriaceae urinary tract infections (UTIs), researchers prospectively studied adults hospitalized with culture-confirmed UTI at 11 university-affiliated hospitals across the U.S. in 2018 and 2019.

The analysis included 527 patients (median age, 52; 62% women). Enterobacteriaceae, most commonly Escherichia coli, were present in 84% of cultures. Among all cultures, the prevalence of ESBL-producing Enterobacteriaceae was 17.2%. Risk factors associated with ESBL-producing Enterobacteriaceae included recent use of antibiotics, recent hospitalization, recent residence in a long-term care facility, and history of antibiotic-resistant infections. Among patients …

Reviewing Author

Benton R. Hunter, MD

Disclosures

Leadership Positions in Professional SocietiesSociety for Academic Emergency Medicine (Chair, Evidence Based Healthcare Interest Group)

Benton R. Hunter, MD

Disclosures

Leadership Positions in Professional SocietiesSociety for Academic Emergency Medicine (Chair, Evidence Based Healthcare Interest Group)

Extended-Spectrum Beta-Lactamase–Producing Bacteria in Patients Hospitalized for UTI

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Reviewing Author