Neurologic Disorders Among Prospectively Followed Inpatients with COVID-19

In a prospective health system–wide study, 13.5% of patients with COVID-19 developed a new neurologic disorder, most commonly encephalopathy, seizures, and stroke, that was often associated with critical illness.

In the early months of the COVID-19 pandemic, various neurologic disorders were associated with SARS-CoV-2 infection in individual case reports, limited case series, and cohort studies. These include encephalopathy, ischemic stroke (including stroke of the young), and Guillain-Barré syndrome. Few prospective data are available based on standard neurologic-syndrome and COVID-19 definitions. Now, researchers have prospectively identified and followed 4491 inpatients hospitalized with COVID-19 (confirmed by reverse transcription polymerase chain reaction [RT-PCR] testing for SARS-CoV-2) at four hospitals within the same New York City health system over a 10-week period.

Of the patients, 606 (13.5%) had a new neurologic disorder per neurologist …

Reviewing Author

John C. Probasco, MD

Disclosures

Grant/Research Support Genetech/Roche

Editorial BoardsThe Neurohospitalist

Leadership Positions in Professional SocietiesNeurohospitalist Society (President; Chair, Research Subcommittee)

John C. Probasco, MD

Disclosures

Grant/Research Support Genetech/Roche

Editorial BoardsThe Neurohospitalist

Leadership Positions in Professional SocietiesNeurohospitalist Society (President; Chair, Research Subcommittee)

Neurologic Disorders Among Prospectively Followed Inpatients with COVID-19

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Reviewing Author