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This update to the 2006 IDSA and 2007 AAN guidelines on the management of Lyme disease used current guideline development methodology. These guidelines do not address other tickborne infections.
As before, doxycycline is recommended for antibiotic prophylaxis after high-risk tick bites.
Treat patients with erythema migrans following Ixodes scapularis tick bites. No recommendation for or against antibiotic therapy is made for rash following lone star tick bites.
Use intravenous (IV) ceftriaxone, cefotaxime, or penicillin or oral doxycycline for ac…