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Neurologic symptoms in adults with COVID-19 are well described and range from headache and anosmia to acute encephalitis, transverse myelitis, and stroke. Severe COVID-19 is much less common in children, and detailed information is limited. To define neurologic symptoms and predict neurologic outcomes in affected children, researchers reviewed records from the Overcoming COVID-19 network of 1695 children and adolescents <21 years of age hospitalized with either severe COVID-19 or multisystem inflammatory syndrome in children (MIS-C) at 61 hospitals across 31 states from March 15 through December 15, 2020.
Findings include the following:
Of the children, 365 (22%) had neurologic involvement, about half of whom had no underlying condition. Howe…