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Many studies have established that dietary sodium intake affects blood pressure (BP). To examine a remaining question about their dose–response relationship, investigators conducted a meta-analysis of 85 trials that assessed dietary sodium intake and BP; most studies enrolled people with hypertension.
Sodium intake ranged from 0.4 to 7.6 g/day, and follow-up lasted from 4 weeks to 36 months. Overall, a linear relationship was identified between sodium intake and systolic and diastolic BPs. For every 100 mmol/day reduction in urinary sodium excretion (87 mmol/day corresponds to 2 g/day), mean systolic BP decreased by 5.56 mm Hg and mean diastolic BP decreased by 2.33 mm Hg. The curve did not flatten at the bottom or top of the range. The pres…