Does Taking More Medications Have Consequences in Older Persons Living with HIV?

In a cross-sectional study of PLWH 50 and older, taking >15 medications was significantly associated with lower chances of viral suppression.

As the life expectancy of persons living with HIV (PLWH) lengthens thanks to modern antiretroviral therapy, issues related to aging and management of co-morbidities assume increasing importance. Managing aging PLWH often involves treatment of a wide variety of common conditions (i.e., hypertension, hyperlipidemia, cardiovascular disease, diabetes, COPD, osteoporosis, degenerative joint diseases, chronic pain, depression, and anxiety), necessitating prescription of numerous medications and leading to drug interactions, adverse reactions, and decreased adherence to antiretrovirals. Investigators at one academic medical center evaluated 612 PLWH aged >50 (median age, 57; 55% white; 84% male) receiving antiretroviral therapy; the analysis focus…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Does Taking More Medications Have Consequences in Older Persons Living with HIV?

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Reviewing Author