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Many patients with subclinical hypothyroidism (i.e., elevated thyroid-stimulating hormone [TSH] but normal free thyroxine levels) have various symptoms that they — or their clinicians — attribute to thyroid dysfunction. Nevertheless, prescribing levothyroxine to such patients does not, on average, improve symptoms (NEJM JW Gen Med Jun 1 2020 and Ann Intern Med 2020; 172:709). To explore further whether symptoms in patients with subclinical hypothyroidism truly are thyroid related or simply incidental, Danish researchers compared the prevalence of 13 symptoms in 376 people with subclinical hypothyroidism and in 7619 euthyroid controls. In previous research by the same group, these specific symptoms were significantly more prevalent in overtl…